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Being given a medicine that holds no licence for your condition can feel like being experimented on. Usually it means the evidence is decent but thinner than a licence demands.
Bupropion is the common case. It helps some people with attention difficulties, often alongside a stimulant, and it never gained the indication, so…
Medication does not simply turn the brain up. On scans the regions that should be busy during a task get busier, and the ones that should stay quiet settle.
That detail matters more than it sounds. It says the trouble is one of aim rather than a shortage of effort, which is the opposite of what many…
Watch someone on a laboratory stop task and two things move together on medication: the fidgeting drops and the stopping gets more accurate.
Holding still and holding back turn out to run on the same machinery. That is why inhibition sits underneath so much else, from waiting your turn to…
In simulator work the biggest improvements on medication show up in the drivers who were worst without it: stopping properly, slowing for an amber, actually looking around.
That pattern is quietly reassuring. A drug that made everyone sharper would lift the good drivers as well, and this does not look like that. It looks…
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